Efficient targeted tumor imaging and secreted endostatin gene delivery by anti-CD105 immunoliposomes
نویسندگان
چکیده
منابع مشابه
Efficient targeted tumor imaging and secreted endostatin gene delivery by anti-CD105 immunoliposomes
BACKGROUND Anti-CD105 mAb-conjugated immunoliposomes, loaded with secreted mouse endostatin gene, were developed for targeted tumor imaging and antiangiogenic gene therapy. METHODS The liposomes were investigated for size, zeta-potential, lipid content, antibody binding ability, and pcDNA loading capacity. The ability of immunoliposomes to target tumor-derived endothelial cells and perform ge...
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ژورنال
عنوان ژورنال: Journal of Experimental & Clinical Cancer Research
سال: 2018
ISSN: 1756-9966
DOI: 10.1186/s13046-018-0712-8